Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

Donna MacMillan; J Murray; Helen F. Sneddon; Craig Jamieson; Allan Watson

doi:10.1039/c2gc36900a

Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

Donna MacMillan, J Murray, Helen F. Sneddon, Craig Jamieson, Allan Watson

Pure And Applied Chemistry

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126 Citations (Scopus)

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Abstract

A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide

Original language	English
Pages (from-to)	596-600
Number of pages	5
Journal	Green Chemistry
Volume	15
Issue number	3
Early online date	19 Dec 2012
DOIs	https://doi.org/10.1039/c2gc36900a
Publication status	Published - 2013

Keywords

coupling reactions
coupling agents
solvents
amide

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10.1039/c2gc36900a

C2gc36900aFinal published version, 886 KB

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title = "Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide",

abstract = "A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide",

keywords = "coupling reactions, coupling agents, solvents, amide",

author = "Donna MacMillan and J Murray and Sneddon, {Helen F.} and Craig Jamieson and Allan Watson",

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AU - Murray, J

AU - Sneddon, Helen F.

AU - Jamieson, Craig

AU - Watson, Allan

PY - 2013

Y1 - 2013

N2 - A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide

AB - A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide

KW - coupling reactions

KW - coupling agents

KW - solvents

KW - amide

U2 - 10.1039/c2gc36900a

DO - 10.1039/c2gc36900a

M3 - Article

SN - 1463-9262

VL - 15

SP - 596

EP - 600

JO - Green Chemistry

JF - Green Chemistry

IS - 3

ER -

Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

Abstract

Keywords

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