Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

N. Kearney, L. McCann, J. Norrie, L. Taylor, P. Gray, M. McGee-Lennon, M. Sage, M. Miller, Roma Maguire

Research output: Contribution to journalArticle

131 Citations (Scopus)

Abstract

Objectives: To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer. Design: A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial. Setting: Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals. Participants: One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy. Interventions: A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©). Main outcome measures: Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea). Results: There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio∈=∈2.29, 95%CI∈=∈1.04 to 5.05, P∈=∈0.040) and reports of hand-foot syndrome were on average lower in the control group (odds ratio control/intervention∈=∈0.39, 95%CI∈=∈0.17 to 0.92, P∈=∈0.031). Conclusion: The study demonstrates that ASyMS © can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

LanguageEnglish
Pages437-444
Number of pages8
JournalSupportive Care in Cancer
Volume17
Issue number4
Early online date25 Oct 2008
DOIs
Publication statusPublished - 30 Apr 2009

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Cell Phones
Hand-Foot Syndrome
Drug Therapy
Fatigue
Colorectal Neoplasms
Lung Neoplasms
Mucositis
Breast Neoplasms
Control Groups
Nausea
Vomiting
Diarrhea
Odds Ratio
District Hospitals
Outpatients
Randomized Controlled Trials
Outcome Assessment (Health Care)
Morbidity
Incidence
Neoplasms

Keywords

  • assessment
  • chemotherapy
  • symptoms
  • technology

Cite this

Kearney, N. ; McCann, L. ; Norrie, J. ; Taylor, L. ; Gray, P. ; McGee-Lennon, M. ; Sage, M. ; Miller, M. ; Maguire, Roma. / Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity. In: Supportive Care in Cancer. 2009 ; Vol. 17, No. 4. pp. 437-444.
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Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity. / Kearney, N.; McCann, L.; Norrie, J.; Taylor, L.; Gray, P.; McGee-Lennon, M.; Sage, M.; Miller, M.; Maguire, Roma.

In: Supportive Care in Cancer, Vol. 17, No. 4, 30.04.2009, p. 437-444.

Research output: Contribution to journalArticle

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AU - Norrie, J.

AU - Taylor, L.

AU - Gray, P.

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AU - Maguire, Roma

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