Euphorbia helioscopia: chemical constituents and biological activities

Abou-El-Hamd H. Mohamed, Mohamed-Elamir F. Hegazy, Mahmoud F. M. Moustafa, Magdi A. El-Sayed, Ibrahim B. Abdel-Farid, Abeer M. Esmail, Mohamed H. Abdelrazik, Naglaa S. Salaheldin, Gomah Nenaah, Tarik A. Mohamed, Abdelaaty A. Shahat, Joe Karchesy, Hisashi Matsuda, Paul W. Pare

Research output: Contribution to journalArticle

Abstract

Euphorbia, the largest genus in the spurge family “Euphorbiaceae” with more than 2000 species and is subdivided into many subgenera and sections. Several species of the genus Euphorbia have been extensively studied for their antiviral, antitumor, cytotoxic, antimicrobial and pesticidal activities. Based on traditional information, Euphorbia helioscopia has been widely used in the traditional folk medicine in China and Turkey. Up to now, 30 diterpenoids have been isolated and structurally characterized from this plant. The aim of the present work is to review all the available scientific literatures published on E. helioscopia. The focus will be on the chemical constitutions that have been identified from this species, in addition, all the reported biological, pharmacological and toxicological activities of different extracts and isolates from this species have been included. The paper recommends the need for further investigations regarding the environmental and mammalian safety of E. helioscopia for safer using in different biological and therapeutic applications. Keywords: Euphorbia helioscopia, chemical constituents, terpenes, flavonoids, volatile oil, biological activities
Original languageEnglish
Number of pages13
JournalInternational Journal of Phytopharmacology
Volume3
Publication statusPublished - 1 Jan 2012

Fingerprint

Euphorbia
Traditional Medicine
Euphorbiaceae
Literature
Diterpenes
Constitution and Bylaws
Terpenes
Volatile Oils
Turkey
Flavonoids
Toxicology
Antiviral Agents
China
Pharmacology
Safety

Keywords

  • Euphorbia helioscopia
  • chemical constituents
  • terpenes
  • flavonoids
  • volatile oil
  • biological activities

Cite this

Mohamed, A-E-H. H., Hegazy, M-E. F., Moustafa, M. F. M., El-Sayed, M. A., Abdel-Farid, I. B., Esmail, A. M., ... Pare, P. W. (2012). Euphorbia helioscopia: chemical constituents and biological activities. International Journal of Phytopharmacology, 3.
Mohamed, Abou-El-Hamd H. ; Hegazy, Mohamed-Elamir F. ; Moustafa, Mahmoud F. M. ; El-Sayed, Magdi A. ; Abdel-Farid, Ibrahim B. ; Esmail, Abeer M. ; Abdelrazik, Mohamed H. ; Salaheldin, Naglaa S. ; Nenaah, Gomah ; Mohamed, Tarik A. ; Shahat, Abdelaaty A. ; Karchesy, Joe ; Matsuda, Hisashi ; Pare, Paul W. / Euphorbia helioscopia : chemical constituents and biological activities. In: International Journal of Phytopharmacology. 2012 ; Vol. 3.
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Mohamed, A-E-HH, Hegazy, M-EF, Moustafa, MFM, El-Sayed, MA, Abdel-Farid, IB, Esmail, AM, Abdelrazik, MH, Salaheldin, NS, Nenaah, G, Mohamed, TA, Shahat, AA, Karchesy, J, Matsuda, H & Pare, PW 2012, 'Euphorbia helioscopia: chemical constituents and biological activities', International Journal of Phytopharmacology, vol. 3.

Euphorbia helioscopia : chemical constituents and biological activities. / Mohamed, Abou-El-Hamd H.; Hegazy, Mohamed-Elamir F.; Moustafa, Mahmoud F. M.; El-Sayed, Magdi A.; Abdel-Farid, Ibrahim B.; Esmail, Abeer M.; Abdelrazik, Mohamed H. ; Salaheldin, Naglaa S.; Nenaah, Gomah; Mohamed, Tarik A.; Shahat, Abdelaaty A.; Karchesy, Joe; Matsuda, Hisashi; Pare, Paul W.

In: International Journal of Phytopharmacology, Vol. 3, 01.01.2012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Euphorbia helioscopia

T2 - chemical constituents and biological activities

AU - Mohamed, Abou-El-Hamd H.

AU - Hegazy, Mohamed-Elamir F.

AU - Moustafa, Mahmoud F. M.

AU - El-Sayed, Magdi A.

AU - Abdel-Farid, Ibrahim B.

AU - Esmail, Abeer M.

AU - Abdelrazik, Mohamed H.

AU - Salaheldin, Naglaa S.

AU - Nenaah, Gomah

AU - Mohamed, Tarik A.

AU - Shahat, Abdelaaty A.

AU - Karchesy, Joe

AU - Matsuda, Hisashi

AU - Pare, Paul W.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Euphorbia, the largest genus in the spurge family “Euphorbiaceae” with more than 2000 species and is subdivided into many subgenera and sections. Several species of the genus Euphorbia have been extensively studied for their antiviral, antitumor, cytotoxic, antimicrobial and pesticidal activities. Based on traditional information, Euphorbia helioscopia has been widely used in the traditional folk medicine in China and Turkey. Up to now, 30 diterpenoids have been isolated and structurally characterized from this plant. The aim of the present work is to review all the available scientific literatures published on E. helioscopia. The focus will be on the chemical constitutions that have been identified from this species, in addition, all the reported biological, pharmacological and toxicological activities of different extracts and isolates from this species have been included. The paper recommends the need for further investigations regarding the environmental and mammalian safety of E. helioscopia for safer using in different biological and therapeutic applications. Keywords: Euphorbia helioscopia, chemical constituents, terpenes, flavonoids, volatile oil, biological activities

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KW - Euphorbia helioscopia

KW - chemical constituents

KW - terpenes

KW - flavonoids

KW - volatile oil

KW - biological activities

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M3 - Article

VL - 3

JO - International Journal of Phytopharmacology

JF - International Journal of Phytopharmacology

SN - 0975-9328

ER -

Mohamed A-E-HH, Hegazy M-EF, Moustafa MFM, El-Sayed MA, Abdel-Farid IB, Esmail AM et al. Euphorbia helioscopia: chemical constituents and biological activities. International Journal of Phytopharmacology. 2012 Jan 1;3.