Establishing and prioritizing research questions for the treatment of alopecia areata: the Alopecia Areata Priority Setting Partnership

A.E. Macbeth, J. Tomlinson, A.G. Messenger, K. Moore-Millar, C. Michaelides, A.R. Shipman, J.M. Kassim, J.R. Brockley, W. Szczecinska, P. Farrant, R. Robinson, J. Rodgers, J. Chambers, S. Upadhyaya, M.J. Harries

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. Objectives: To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals. Methods: An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process. Results:In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into ‘indicative uncertainties’ following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed. Conclusions:
We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.
LanguageEnglish
Pages1316-1320
Number of pages5
JournalThe British journal of dermatology
Volume176
Issue number5
Early online date16 Apr 2017
DOIs
Publication statusPublished - 31 May 2017

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Alopecia Areata
Uncertainty
Alopecia
Research
Caregivers
Therapeutics
Delivery of Health Care
Research Personnel
Exercise
Education

Keywords

  • alopecia areata
  • autoimmune hair loss
  • hair loss

Cite this

Macbeth, A.E. ; Tomlinson, J. ; Messenger, A.G. ; Moore-Millar, K. ; Michaelides, C. ; Shipman, A.R. ; Kassim, J.M. ; Brockley, J.R. ; Szczecinska, W. ; Farrant, P. ; Robinson, R. ; Rodgers, J. ; Chambers, J. ; Upadhyaya, S. ; Harries, M.J. / Establishing and prioritizing research questions for the treatment of alopecia areata : the Alopecia Areata Priority Setting Partnership. In: The British journal of dermatology. 2017 ; Vol. 176, No. 5. pp. 1316-1320.
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abstract = "Background: Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. Objectives: To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals. Methods: An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process. Results:In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into ‘indicative uncertainties’ following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed. Conclusions:We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.",
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Macbeth, AE, Tomlinson, J, Messenger, AG, Moore-Millar, K, Michaelides, C, Shipman, AR, Kassim, JM, Brockley, JR, Szczecinska, W, Farrant, P, Robinson, R, Rodgers, J, Chambers, J, Upadhyaya, S & Harries, MJ 2017, 'Establishing and prioritizing research questions for the treatment of alopecia areata: the Alopecia Areata Priority Setting Partnership' The British journal of dermatology, vol. 176, no. 5, pp. 1316-1320. https://doi.org/10.1111/bjd.15099

Establishing and prioritizing research questions for the treatment of alopecia areata : the Alopecia Areata Priority Setting Partnership. / Macbeth, A.E.; Tomlinson, J.; Messenger, A.G.; Moore-Millar, K.; Michaelides, C.; Shipman, A.R.; Kassim, J.M.; Brockley, J.R.; Szczecinska, W.; Farrant, P.; Robinson, R.; Rodgers, J.; Chambers, J.; Upadhyaya, S.; Harries, M.J.

In: The British journal of dermatology, Vol. 176, No. 5, 31.05.2017, p. 1316-1320.

Research output: Contribution to journalArticle

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T1 - Establishing and prioritizing research questions for the treatment of alopecia areata

T2 - The British journal of dermatology

AU - Macbeth, A.E.

AU - Tomlinson, J.

AU - Messenger, A.G.

AU - Moore-Millar, K.

AU - Michaelides, C.

AU - Shipman, A.R.

AU - Kassim, J.M.

AU - Brockley, J.R.

AU - Szczecinska, W.

AU - Farrant, P.

AU - Robinson, R.

AU - Rodgers, J.

AU - Chambers, J.

AU - Upadhyaya, S.

AU - Harries, M.J.

N1 - This is the peer reviewed version of the following article: Macbeth, A. E., Tomlinson, J., Messenger, A. G., Moore-Millar, K., Michaelides, C., Shipman, A. R., ... Harries, M. J. (2017). Establishing and prioritizing research questions for the treatment of alopecia areata: the Alopecia Areata Priority Setting Partnership. The British journal of dermatology, 176(5), 1316-1320. DOI: 10.1111/bjd.15099, which has been published in final form at http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjd.15099/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

PY - 2017/5/31

Y1 - 2017/5/31

N2 - Background: Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. Objectives: To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals. Methods: An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process. Results:In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into ‘indicative uncertainties’ following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed. Conclusions:We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.

AB - Background: Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. Objectives: To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals. Methods: An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process. Results:In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into ‘indicative uncertainties’ following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed. Conclusions:We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.

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KW - autoimmune hair loss

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