Enzyme-responsive materials: a new class of smart biomaterials

Research output: Contribution to journalArticle

306 Citations (Scopus)

Abstract

Enzyme-responsive materials (ERMs) are a new class of smart materials that undergo macroscopic transitions when triggered by selective catalytic actions of enzymes. The use of enzymes as stimuli to trigger mechanical responses in materials opens up a number of possible applications in biology and medicine. Three different classes of ERMs are described, based on supramolecular assemblies, chemically crosslinked gels and (nanoparticle) surfaces. Potential applications in regenerative medicine, diagnostics, and drug delivery are discussed.

LanguageEnglish
Pages2217-2225
Number of pages9
JournalJournal of Materials Chemistry
Volume16
Issue number23
Early online date18 Apr 2006
DOIs
Publication statusPublished - 2006

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Biocompatible Materials
Biomaterials
Enzymes
Intelligent materials
Drug delivery
Medicine
Gels
Nanoparticles

Keywords

  • enzyme-responsive materials
  • new class
  • smart biomaterials

Cite this

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Enzyme-responsive materials : a new class of smart biomaterials. / Ulijn, R V .

In: Journal of Materials Chemistry , Vol. 16, No. 23, 2006, p. 2217-2225.

Research output: Contribution to journalArticle

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