Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

Gabriele Rucinskaite, Sebastian A. Thompson, Sureyya Paterson, Roberto De La Rica

Research output: Contribution to journalArticle

12 Citations (Scopus)
25 Downloads (Pure)

Abstract

A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide-integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose).

Original languageEnglish
Pages (from-to)5404-5407
Number of pages4
JournalNanoscale
Volume9
Issue number17
Early online date12 Apr 2017
DOIs
Publication statusPublished - 7 May 2017

Keywords

  • nanoparticles
  • cell membranes
  • peptides

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