Enhanced attachment of acanthamoeba to extended-wear silicone hydrogel contact lenses: a new risk factor for infection?

T.K. Beattie, A. Tomlinson, A. McFadyen, D. Seal, A.M. Grimason

Research output: Contribution to journalArticle

55 Citations (Scopus)


Acanthamoebal attachment to the S-H lenses was significantly greater than to the conventional hydrogel. Liquid-cultured trophozoites demonstrated a higher affinity for the lenses tested. Wear and bacterial biofilm coating had no effect on attachment to S-H lenses. The increased attachment found with the S-H lens may be an inherent characteristic of the polymer or a side effect of the surface treatment procedure to which the lenses are exposed. It is possible that S-H lenses are at greater risk of promoting Acanthamoeba infection if exposed to the organism because of the enhanced attachment characteristic of this new material.
Original languageEnglish
Pages (from-to)765-771
Number of pages6
JournalBMC Ophthalmology
Issue number4
Publication statusPublished - 2003


  • microbiology
  • contact lens
  • ophthalmology
  • acanthamoeba

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