Energy transfer between a biological labelling dye and gold nanorods

Chris  Racknor; Mahi R  Singh; Yinan Zhang; David J S Birch; Yu Chen

doi:10.1088/2050-6120/2/1/015002

Energy transfer between a biological labelling dye and gold nanorods

Chris Racknor, Mahi R Singh, Yinan Zhang, David J S Birch, Yu Chen

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Abstract

We have demonstrated energy transfer between a biological labelling dye (Alexa Fluor 405) and gold nanorods experimentally and theoretically. The fluorescence lifetime imaging microscopy and density matrix method are used to study a hybrid system of dye and nanorods under one- and two-photon excitations. Energy transfer between dye and nanorods via the dipole–dipole interaction is found to cause a decrease in the fluorescence lifetime change. Enhanced energy transfer from dye to nanorods is measured in the presence of an increased density of nanorods. This study has potential applications in fluorescence lifetime-based intra-cellular sensing of bio-analytes as well as nuclear targeting cancer therapy

Original language	English
Article number	015002
Number of pages	6
Journal	Methods and Applications in Fluorescence
Volume	2
Issue number	1
Early online date	15 Nov 2013
DOIs	https://doi.org/10.1088/2050-6120/2/1/015002
Publication status	Published - 1 Mar 2014

Keywords

thin films
energy transfer
gold nanorods
biological labelling dye
biological physics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1088/2050-6120/2/1/015002

racknor-singh-zhang-birch-chen-FL2013-edit-1Submitted manuscript, 377 KB

Cite this

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title = "Energy transfer between a biological labelling dye and gold nanorods",

abstract = "We have demonstrated energy transfer between a biological labelling dye (Alexa Fluor 405) and gold nanorods experimentally and theoretically. The fluorescence lifetime imaging microscopy and density matrix method are used to study a hybrid system of dye and nanorods under one- and two-photon excitations. Energy transfer between dye and nanorods via the dipole–dipole interaction is found to cause a decrease in the fluorescence lifetime change. Enhanced energy transfer from dye to nanorods is measured in the presence of an increased density of nanorods. This study has potential applications in fluorescence lifetime-based intra-cellular sensing of bio-analytes as well as nuclear targeting cancer therapy",

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T1 - Energy transfer between a biological labelling dye and gold nanorods

AU - Racknor, Chris

AU - Singh, Mahi R

AU - Zhang, Yinan

AU - Birch, David J S

AU - Chen, Yu

PY - 2014/3/1

Y1 - 2014/3/1

N2 - We have demonstrated energy transfer between a biological labelling dye (Alexa Fluor 405) and gold nanorods experimentally and theoretically. The fluorescence lifetime imaging microscopy and density matrix method are used to study a hybrid system of dye and nanorods under one- and two-photon excitations. Energy transfer between dye and nanorods via the dipole–dipole interaction is found to cause a decrease in the fluorescence lifetime change. Enhanced energy transfer from dye to nanorods is measured in the presence of an increased density of nanorods. This study has potential applications in fluorescence lifetime-based intra-cellular sensing of bio-analytes as well as nuclear targeting cancer therapy

AB - We have demonstrated energy transfer between a biological labelling dye (Alexa Fluor 405) and gold nanorods experimentally and theoretically. The fluorescence lifetime imaging microscopy and density matrix method are used to study a hybrid system of dye and nanorods under one- and two-photon excitations. Energy transfer between dye and nanorods via the dipole–dipole interaction is found to cause a decrease in the fluorescence lifetime change. Enhanced energy transfer from dye to nanorods is measured in the presence of an increased density of nanorods. This study has potential applications in fluorescence lifetime-based intra-cellular sensing of bio-analytes as well as nuclear targeting cancer therapy

KW - thin films

KW - energy transfer

KW - gold nanorods

KW - biological labelling dye

KW - biological physics

UR - http://iopscience.iop.org/2050-6120/

U2 - 10.1088/2050-6120/2/1/015002

DO - 10.1088/2050-6120/2/1/015002

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VL - 2

JO - Methods and Applications in Fluorescence

JF - Methods and Applications in Fluorescence

IS - 1

M1 - 015002

ER -

Energy transfer between a biological labelling dye and gold nanorods

Abstract

Keywords

UN SDGs

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NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture

Cite this

Energy transfer between a biological labelling dye and gold nanorods

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Projects

NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture

Cite this