Encephalitis in mice with congenital ocular toxoplasmosis

D.I. Graham, J. Hay, W.M. Hutchison, J.C. Siim

Research output: Contribution to journalArticle

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Abstract

The brains of mice with congenital ocular toxoplasmosis were examined histologically. Toxoplasma tissue cysts and a subacute/chronic meningo-encephalitis were present in the brains of all infected mice. The findings were very similar to those seen in human congenital toxoplasmosis. The murine model of congenital toxoplasmic encephalitis described in this paper will be valuable in the study of the pathogenesis, natural history and treatment of this condition.
Original languageEnglish
Pages (from-to)265-277
Number of pages12
JournalJournal of Pathology
Volume142
Issue number4
DOIs
Publication statusPublished - 1984

Fingerprint

Ocular Toxoplasmosis
Congenital Toxoplasmosis
Encephalitis
Toxoplasma
Brain
Natural History
Cysts

Keywords

  • toxoplasmosis
  • congenital infection
  • encephalitis
  • ocular disease
  • mice

Cite this

Graham, D. I., Hay, J., Hutchison, W. M., & Siim, J. C. (1984). Encephalitis in mice with congenital ocular toxoplasmosis. Journal of Pathology, 142(4), 265-277. https://doi.org/10.1002/path.1711420405
Graham, D.I. ; Hay, J. ; Hutchison, W.M. ; Siim, J.C. / Encephalitis in mice with congenital ocular toxoplasmosis. In: Journal of Pathology. 1984 ; Vol. 142, No. 4. pp. 265-277.
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Graham, DI, Hay, J, Hutchison, WM & Siim, JC 1984, 'Encephalitis in mice with congenital ocular toxoplasmosis', Journal of Pathology, vol. 142, no. 4, pp. 265-277. https://doi.org/10.1002/path.1711420405

Encephalitis in mice with congenital ocular toxoplasmosis. / Graham, D.I.; Hay, J.; Hutchison, W.M.; Siim, J.C.

In: Journal of Pathology, Vol. 142, No. 4, 1984, p. 265-277.

Research output: Contribution to journalArticle

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