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Abstract
The study aimed to develop a rapid model using gProms Formulated Products for a proprietary single polymorph active pharmaceutical ingredient (API) crystallisation at small scale for early process understanding. The model outcomes are then later used to inform the experimental design of continuous crystallisation for multi-addition antisolvent and cooling crystallization in both continuous oscillatory
baffled reactor (COBC) and mixed-suspension and mixed- product removal (MSMPR) crystalliser
baffled reactor (COBC) and mixed-suspension and mixed- product removal (MSMPR) crystalliser
Original language | English |
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Number of pages | 1 |
Publication status | Published - 3 Nov 2019 |
Event | American Association of Pharmaceutical Scientists PharmSci 360, 2019 - San Antonio, United States Duration: 3 Nov 2019 → 7 Nov 2019 |
Conference
Conference | American Association of Pharmaceutical Scientists PharmSci 360, 2019 |
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Abbreviated title | AAPS PharmSci 360, 2019 |
Country/Territory | United States |
City | San Antonio |
Period | 3/11/19 → 7/11/19 |
Keywords
- crystallisation
- reactor geometries
- continuous crystallisation
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Dive into the research topics of 'Enabling model-predictive design: rapid development of a PBM for an anti-solvent and cooling crystallisation in two different reactor geometries'. Together they form a unique fingerprint.Projects
- 1 Finished
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CMAC PDRA (year 2) Keddon Powell
Florence, A. (Principal Investigator)
31/08/16 → 30/09/19
Project: Research