Enabling future manufacture of dose forms: screening tools for an HME-3D printing process

E. Prasad; J. Robertson; G. Halbert

Enabling future manufacture of dose forms: screening tools for an HME-3D printing process

E. Prasad, J. Robertson, G. Halbert

Strathclyde Institute Of Pharmacy And Biomedical Sciences

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Abstract

Linking a hot-melt-extrusion (HME) process to 3D printing offers the ability for rapid prototyping of dose forms, whilst also allowing for personalisation of the dosage form to the patient's needs. However, process development can be lengthy and laborious since current technology involves process development for the HME and fused filament fabrication (FFF) process via the filament as an intermediate product. This work aims to develop screening tools to understand and predict API-polymer behaviour in HME and FFF processes and therefore reducing development time and resource.

Original language	English
Publication status	Published - 23 Oct 2019
Event	CMAC UK Showcase - CMAC Future Manufacturing Research Hub, Strathclyde Institute of Pharmacy and Biomedical Sciences, Glasgow, United Kingdom Duration: 23 Oct 2019 → 23 Oct 2019

Conference

Conference	CMAC UK Showcase
Country/Territory	United Kingdom
City	Glasgow
Period	23/10/19 → 23/10/19

Keywords

hot-melt-extrusion
3D printing
HME-3D printing

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Prasad-etal-CMAC2019-Enabling-future-manufacture-of-dose-forms-screening-tools-for-an-HME-3DFinal published version, 1.15 MB

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title = "Enabling future manufacture of dose forms: screening tools for an HME-3D printing process",

abstract = "Linking a hot-melt-extrusion (HME) process to 3D printing offers the ability for rapid prototyping of dose forms, whilst also allowing for personalisation of the dosage form to the patient's needs. However, process development can be lengthy and laborious since current technology involves process development for the HME and fused filament fabrication (FFF) process via the filament as an intermediate product. This work aims to develop screening tools to understand and predict API-polymer behaviour in HME and FFF processes and therefore reducing development time and resource. ",

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AU - Robertson, J.

AU - Halbert, G.

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N2 - Linking a hot-melt-extrusion (HME) process to 3D printing offers the ability for rapid prototyping of dose forms, whilst also allowing for personalisation of the dosage form to the patient's needs. However, process development can be lengthy and laborious since current technology involves process development for the HME and fused filament fabrication (FFF) process via the filament as an intermediate product. This work aims to develop screening tools to understand and predict API-polymer behaviour in HME and FFF processes and therefore reducing development time and resource.

AB - Linking a hot-melt-extrusion (HME) process to 3D printing offers the ability for rapid prototyping of dose forms, whilst also allowing for personalisation of the dosage form to the patient's needs. However, process development can be lengthy and laborious since current technology involves process development for the HME and fused filament fabrication (FFF) process via the filament as an intermediate product. This work aims to develop screening tools to understand and predict API-polymer behaviour in HME and FFF processes and therefore reducing development time and resource.

KW - hot-melt-extrusion

KW - 3D printing

KW - HME-3D printing

M3 - Poster

T2 - CMAC UK Showcase

Y2 - 23 October 2019 through 23 October 2019

ER -

Enabling future manufacture of dose forms: screening tools for an HME-3D printing process

Abstract

Conference

Keywords

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