Elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2

Osama Idris Gibreel Khreit, Mary Grant, Tong Zhang, Catherine Henderson, David Watson, Oliver Brook Sutcliffe

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30 Citations (Scopus)

Abstract

Describes the elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2
LanguageEnglish
Pages177-185
Number of pages9
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume72
Early online date29 Aug 2012
DOIs
Publication statusPublished - 2013

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Metabolic Networks and Pathways
Liver
Rats
Hepatocytes
monomethylpropion

Keywords

  • nethylmethcathinone
  • rat liver hepatocytes
  • metabolic pathways
  • elucidation

Cite this

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abstract = "Describes the elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2",
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AU - Khreit, Osama Idris Gibreel

AU - Grant, Mary

AU - Zhang, Tong

AU - Henderson, Catherine

AU - Watson, David

AU - Sutcliffe, Oliver Brook

PY - 2013

Y1 - 2013

N2 - Describes the elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2

AB - Describes the elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2

KW - nethylmethcathinone

KW - rat liver hepatocytes

KW - metabolic pathways

KW - elucidation

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