Electrokinetic manipulation of pharmaceutical crystalline compounds

Research output: Contribution to conferencePoster

Abstract

An inhomogeneous direct-current (DC) electric field imposed within pure suspensions exerts a translational force on the crystallised material, which selectively collects on one of the two electrodes. Electric Field Enhanced Crystallisation (EFCE) makes use of this phenomenon to purify and physically separate the solutes in multi-component suspensions[1]. This technique can be divided into three main steps: A motion of the suspended material is induced by the application of an electric field, by increasing the potential difference the material collects on one electrode, and finally the crystals are immobilized upon a reduction of the temperature (cooling crystallisation).

The application of this new technique in complex mixtures and the effects of electric fields on crystallisation are being studied.
Original languageEnglish
Publication statusUnpublished - 22 Jun 2018
EventBACG Annual Conference - University of Limerick, Kimerick, Ireland
Duration: 20 Jun 201822 Jun 2018
Conference number: 49
https://www.bacg.co.uk/event/bacg-49th-annual-conference/

Conference

ConferenceBACG Annual Conference
CountryIreland
CityKimerick
Period20/06/1822/06/18
Internet address

Keywords

  • pharmaceutical crystalline compounds
  • electrokinetic manipulation
  • electric field

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