Effects of electrically induced muscle contraction on flexion reflex in human spinal cord injury

M. Knikou, B.A. Conway

    Research output: Contribution to journalArticlepeer-review

    28 Citations (Scopus)


    Study aims to examine changes in the magnitude of the flexion reflex following functional electrical stimulation (FES) of the rectus femoris (RF) muscle. The incidence of the early component of the flexion reflex (<100 ms) was low, suggesting that this reflex component might be suppressed in SCI. The long latency flexion reflex component (>120 ms) was observed in all subjects during control conditions and following sensorimotor conditioning. FES applied to the RF muscle (above and below MT) in the main induced a significant early and long lasting depression of the long latency flexion reflex. The depression of the flexion reflex was a result of multisensory actions on flexion reflex pathways resulting from the direct and indirect (mechanical) consequences of electrically induced muscle contraction on cutaneous and muscle afferents. Our findings emphasize the importance of sensory feedback mechanisms in modulating flexion reflex excitability, and highlight the need for rehabilitation professionals to consider the central actions of FES-induced afferent feedback when incorporating FES into a rehabilitation program.
    Original languageEnglish
    Pages (from-to)640-648
    Number of pages8
    JournalSpinal Cord
    Issue number11
    Publication statusPublished - 2005


    • FES
    • cutaneous afferents
    • rehabilitation
    • sensorimotor integration
    • bioengineering


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