Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11

R. Pebody, P. Hardelid, D.M. Fleming, J. McMenamin, N. Andrews, C. Robertson, D. R. Thomas, P. SebastianPillai, J. Ellis, W. Carman

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34% (95% CI: -10 - 60%) if vaccinated only with monovalent vaccine in the 2009/10 season; 46% (95% CI: 7 - 69%) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63% (95% CI: 37 - 78%) if vaccinated in both seasons.
LanguageEnglish
Pages8-13
Number of pages6
JournalEurosurveillance
Volume16
Issue number6
Publication statusPublished - 10 Feb 2011

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Pandemics
Human Influenza
Vaccines
Infection
Influenza Vaccines
Vaccination
United Kingdom

Keywords

  • statistics
  • influenza A virus, H1N1 Subtype
  • pandemic influenza
  • influenza
  • vaccination

Cite this

Pebody, R. ; Hardelid, P. ; Fleming, D.M. ; McMenamin, J. ; Andrews, N. ; Robertson, C. ; Thomas, D. R. ; SebastianPillai, P. ; Ellis, J. ; Carman, W. / Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11. In: Eurosurveillance. 2011 ; Vol. 16, No. 6. pp. 8-13.
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title = "Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11",
abstract = "This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34{\%} (95{\%} CI: -10 - 60{\%}) if vaccinated only with monovalent vaccine in the 2009/10 season; 46{\%} (95{\%} CI: 7 - 69{\%}) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63{\%} (95{\%} CI: 37 - 78{\%}) if vaccinated in both seasons.",
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author = "R. Pebody and P. Hardelid and D.M. Fleming and J. McMenamin and N. Andrews and C. Robertson and Thomas, {D. R.} and P. SebastianPillai and J. Ellis and W. Carman",
note = "Funding This work has been undertaken as part of a European Centre for Disease Control and Prevention (ECDC) funded project “I-MOVE”, which is co-ordinated by Epi-Concept (http://www.epiconcept.fr/). Conflicts of interest All authors have completed the Unified Competing Interest form at http://www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare that DM Fleming has received funding to attend influenza related meetings and has received consultancy fees from influenza vaccine manufacturers who might have an interest in the submitted work in the previous 3 years. In addition, The Virus Reference Department of the Health Protection Agency receives funding from a variety of vaccine manufacturers who might have an interest in the submitted work. All other authors declare they have no conflicts of interest.",
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Pebody, R, Hardelid, P, Fleming, DM, McMenamin, J, Andrews, N, Robertson, C, Thomas, DR, SebastianPillai, P, Ellis, J & Carman, W 2011, 'Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11' Eurosurveillance, vol. 16, no. 6, pp. 8-13.

Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11. / Pebody, R.; Hardelid, P.; Fleming, D.M.; McMenamin, J.; Andrews, N.; Robertson, C.; Thomas, D. R.; SebastianPillai, P.; Ellis, J.; Carman, W.

In: Eurosurveillance, Vol. 16, No. 6, 10.02.2011, p. 8-13.

Research output: Contribution to journalArticle

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