Effectiveness of interventions for upper limb recovery after stroke: a systematic review

F. Coupar, P. Langhorne, P.J. Rowe, C. Weir

    Research output: Contribution to conferencePaper

    Abstract

    Background: Upper limb deficits are common following stroke and have a significant impact on disability and health. Rehabilitation interventions for the upper limb usually focus on reducing impairment and increasing function. However, the design and evaluation of such interventions is complex. We carried out a systematic review to identify the effectiveness of interventions targeted at upper limb recovery. Methods: We searched the Cochrane Stroke Group trials register for randomised trials of an intervention aimed specifically at upper limb recovery compared to placebo, no treatment or standard care. We included outcomes related to impaired movement or related functions of the upper limb. Two reviewers allocated each trial to a particular intervention, assessed methodological quality and extracted data. Means and standard deviations were extracted and combined within meta-analyses to derive a standardised mean difference (SMD) and 95% confidence intervals (CI). Results: Ten interventions had more than one relevant randomised controlled trial. A statistically significant result was found in favour of five interventions: EMG biofeedback (SMD 0.41 95% CI 0.05 to 0.77); electrostimulation (SMD 0.31 95% CI 0.06 to 0.56); mental practice/imagery (SMD 0.84 95% CI 0.34 to 1.33); robotics (SMD 0.61 95% 0.30 to 0.92) and constraint induced movement therapy (SMD 0.73 95% CI 0.54 to 0.91). No significant result was found for repetitive task training, spliniting/orthoses, increased intensity, neurophysiological approach (Bobath) or bilateral training. Conclusions: This review is limited by the heterogeneity of the trials, in terms of study design, analysis and quality. Despite the limitations these data provide a concise and informative summary of the available evidence for interventions targeted at upper limb recovery and suggests that a number of interventions may be beneficial for upper limb recovery. This paper was presented at the XVIII European Stroke Conference, in 2009.
    Original languageEnglish
    Publication statusPublished - 2009
    EventXVIII European Stroke Conference - Stockholm, Sweden
    Duration: 26 May 200929 May 2009

    Conference

    ConferenceXVIII European Stroke Conference
    CityStockholm, Sweden
    Period26/05/0929/05/09

    Keywords

    • upper limb recovery
    • stroke
    • rehabilitation

    Cite this

    Coupar, F., Langhorne, P., Rowe, P. J., & Weir, C. (2009). Effectiveness of interventions for upper limb recovery after stroke: a systematic review. Paper presented at XVIII European Stroke Conference, Stockholm, Sweden, .