Abstract
Collagen gels are widely used as matrices for in vitro cell culture and also for a variety of tissue engineering applications. The mechanical properties of matrices have been shown to be important parameters which greatly influence cell
behaviour. For successful support of long term cell growth and function, it is important for matrices to retain their mechanical integrity during the period of use. The presence of cells has been shown to alter matrix properties. The aim of this
study was to investigate the effect of seeding primary hepatocytes on the mechanical properties of collagen hydrogel matrices.
behaviour. For successful support of long term cell growth and function, it is important for matrices to retain their mechanical integrity during the period of use. The presence of cells has been shown to alter matrix properties. The aim of this
study was to investigate the effect of seeding primary hepatocytes on the mechanical properties of collagen hydrogel matrices.
| Original language | English |
|---|---|
| Pages (from-to) | 77 |
| Number of pages | 1 |
| Journal | European Cells and Materials |
| Volume | 28 |
| Issue number | S.4 |
| Publication status | Published - Nov 2014 |
| Event | The 2014 Annual Tissue and Cell Engineering Society (TCES) Meeting - Newcastel university, Newcastle, United Kingdom Duration: 2 Jul 2014 → 4 Jul 2014 |
Keywords
- primary hepatocytes
- rats
- collagen gel matrices
- matrix properties