Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms

I. Timoshkin; J.W. Mackersie; S.J. MacGregor; R.A. Fouracre; J.G. Anderson

doi:10.1109/MODSYM.2004.1433651

Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms

I. Timoshkin, J.W. Mackersie, S.J. MacGregor, R.A. Fouracre, J.G. Anderson

Electronic And Electrical Engineering

Research output: Contribution to conference › Paper

Abstract

The pulsed electric field (PEF) processing of liquid and pumpable products has attracted significant interest from the pulsed power and bioscience research communities due to the nonthermal mechanisms of inactivation which results in preservation of the original characteristics of the product. Although the PEF process has been studied for several decades, the physical mechanisms of the interaction of pulsed electrical fields with microorganisms is still not understood fully. The present work is a study of the dynamics of the electrical field in the PEF treatment chamber with dielectric barriers and in the microorganism's membrane. It was found that the field in the membrane reaches a maximal value which could be two orders of magnitude higher than the original electrical field in the chamber and this value was attained in a time comparable to the Maxwell-Wagner relaxation time, τMW. Thus, the optimal duration of the field pulse during the PEF treatment should be equal to the time τMW

Original language	English
Pages	611-614
Number of pages	3
DOIs	https://doi.org/10.1109/MODSYM.2004.1433651
Publication status	Published - May 2004
Event	26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop - , United Kingdom Duration: 23 May 2004 → 26 May 2004

Conference

Conference	26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop
Country	United Kingdom
Period	23/05/04 → 26/05/04

Keywords

dynamics
development
electrical field
cellular membranes
PEF inactivation
microorganisms

Access to Document

10.1109/MODSYM.2004.1433651

Cite this

Timoshkin, I., Mackersie, J. W., MacGregor, S. J., Fouracre, R. A., & Anderson, J. G. (2004). Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms. 611-614. Paper presented at 26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop , United Kingdom. https://doi.org/10.1109/MODSYM.2004.1433651

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title = "Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms",

abstract = "The pulsed electric field (PEF) processing of liquid and pumpable products has attracted significant interest from the pulsed power and bioscience research communities due to the nonthermal mechanisms of inactivation which results in preservation of the original characteristics of the product. Although the PEF process has been studied for several decades, the physical mechanisms of the interaction of pulsed electrical fields with microorganisms is still not understood fully. The present work is a study of the dynamics of the electrical field in the PEF treatment chamber with dielectric barriers and in the microorganism's membrane. It was found that the field in the membrane reaches a maximal value which could be two orders of magnitude higher than the original electrical field in the chamber and this value was attained in a time comparable to the Maxwell-Wagner relaxation time, τMW. Thus, the optimal duration of the field pulse during the PEF treatment should be equal to the time τMW",

keywords = "dynamics, development, electrical field, cellular membranes, PEF inactivation , microorganisms ",

author = "I. Timoshkin and J.W. Mackersie and S.J. MacGregor and R.A. Fouracre and J.G. Anderson",

year = "2004",

month = may,

doi = "10.1109/MODSYM.2004.1433651",

language = "English",

pages = "611--614",

note = "26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop ; Conference date: 23-05-2004 Through 26-05-2004",

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Timoshkin, I, Mackersie, JW, MacGregor, SJ, Fouracre, RA & Anderson, JG 2004, 'Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms', Paper presented at 26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop , United Kingdom, 23/05/04 - 26/05/04 pp. 611-614. https://doi.org/10.1109/MODSYM.2004.1433651

Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms. / Timoshkin, I.; Mackersie, J.W.; MacGregor, S.J.; Fouracre, R.A.; Anderson, J.G.

2004. 611-614 Paper presented at 26th International Power Modulator Symposium, 2004 and 2004 High-Voltage Workshop , United Kingdom.

Research output: Contribution to conference › Paper

TY - CONF

T1 - Dynamics of the development of an electrical field across cellular membranes-PEF inactivation of microorganisms

AU - Timoshkin, I.

AU - Mackersie, J.W.

AU - MacGregor, S.J.

AU - Fouracre, R.A.

AU - Anderson, J.G.

PY - 2004/5

Y1 - 2004/5

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AB - The pulsed electric field (PEF) processing of liquid and pumpable products has attracted significant interest from the pulsed power and bioscience research communities due to the nonthermal mechanisms of inactivation which results in preservation of the original characteristics of the product. Although the PEF process has been studied for several decades, the physical mechanisms of the interaction of pulsed electrical fields with microorganisms is still not understood fully. The present work is a study of the dynamics of the electrical field in the PEF treatment chamber with dielectric barriers and in the microorganism's membrane. It was found that the field in the membrane reaches a maximal value which could be two orders of magnitude higher than the original electrical field in the chamber and this value was attained in a time comparable to the Maxwell-Wagner relaxation time, τMW. Thus, the optimal duration of the field pulse during the PEF treatment should be equal to the time τMW

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KW - development

KW - electrical field

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KW - PEF inactivation

KW - microorganisms

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