Dynamic combinatorial discovery of a [2]-catenane and its guest-induced conversion into a molecular square host

K.R. West; R.F. Ludlow; P.T. Corbett; P. Besenius; F.M. Mansfeld; P.A.G. Cormack; D.C. Sherrington; J.M. Goodman; Marc C.A. Stuart; Sijbren Otto

doi:10.1021/ja801508q

Dynamic combinatorial discovery of a [2]-catenane and its guest-induced conversion into a molecular square host

K.R. West
, R.F. Ludlow
, P.T. Corbett
, P. Besenius
, F.M. Mansfeld
, P.A.G. Cormack
, D.C. Sherrington
, J.M. Goodman
, Marc C.A. Stuart
, Sijbren Otto

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

A simple water-soluble naphthalenedithiol building block is converted quantitatively into a series of octameric [2]-catenanes, composed of two interlocked molecular squares. When this mixture is re-equilibrated in the presence of an adamantyl ammonium guest, the catenanes disassemble into their macrocyclic components that bind the guest with nanomolar affinity in water.

Original language	English
Pages (from-to)	10834–10835
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	130
Issue number	33
DOIs	https://doi.org/10.1021/ja801508q
Publication status	Published - 20 Aug 2008

Keywords

molecular science
molecular squares
adamantyl ammonium

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10.1021/ja801508q

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West, K. R., Ludlow, R. F., Corbett, P. T., Besenius, P., Mansfeld, F. M., Cormack, P. A. G., Sherrington, D. C., Goodman, J. M., Stuart, M. C. A., & Otto, S. (2008). Dynamic combinatorial discovery of a [2]-catenane and its guest-induced conversion into a molecular square host. Journal of the American Chemical Society, 130(33), 10834–10835. https://doi.org/10.1021/ja801508q

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AU - Besenius, P.

AU - Mansfeld, F.M.

AU - Cormack, P.A.G.

AU - Sherrington, D.C.

AU - Goodman, J.M.

AU - Stuart, Marc C.A.

AU - Otto, Sijbren

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AB - A simple water-soluble naphthalenedithiol building block is converted quantitatively into a series of octameric [2]-catenanes, composed of two interlocked molecular squares. When this mixture is re-equilibrated in the presence of an adamantyl ammonium guest, the catenanes disassemble into their macrocyclic components that bind the guest with nanomolar affinity in water.

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KW - adamantyl ammonium

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JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 33

ER -

Dynamic combinatorial discovery of a [2]-catenane and its guest-induced conversion into a molecular square host

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Keywords

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