TY - UNPB
T1 - Dye-free retinal angiography using blood-oxygenation modulation
AU - MacKenzie, L.E.
AU - Choudhary, T.R.
AU - Fernandez Ramos, J.
AU - Benjamin, N.
AU - Delles, C.
AU - Harvey, A.R.
PY - 2018/12/6
Y1 - 2018/12/6
N2 - Fluorescence angiography (FA) is widely used for studying and diagnosing abnormalities in the retinal blood circulation, but has associated risks of nausea, skin irritation, and even death. We describe a new non-invasive angiography technique: Blood Oxygenation Modulation Angiography, in which multispectral imaging of a transient perturbation in blood-oxygen saturation, yields angiography sequences similar to FA, including key features such as sequential filling of choroidal and retinal-vessels, which underpin assessment of circulation health. This is the first non-invasive angiography technique capable of visualizing these circulation features.
AB - Fluorescence angiography (FA) is widely used for studying and diagnosing abnormalities in the retinal blood circulation, but has associated risks of nausea, skin irritation, and even death. We describe a new non-invasive angiography technique: Blood Oxygenation Modulation Angiography, in which multispectral imaging of a transient perturbation in blood-oxygen saturation, yields angiography sequences similar to FA, including key features such as sequential filling of choroidal and retinal-vessels, which underpin assessment of circulation health. This is the first non-invasive angiography technique capable of visualizing these circulation features.
KW - fluorescence angiography
KW - retinal blood circulation
KW - blood-oxygen saturation
U2 - 10.1101/485839
DO - 10.1101/485839
M3 - Working Paper/Preprint
SP - 1
EP - 18
BT - Dye-free retinal angiography using blood-oxygenation modulation
CY - New York
ER -