This paper describes a methodology for the modification of phase transition temperatures using (+/-)-4 `-methylmethcathinone solid solutions as an exemplar. This method serves to show that by varying the composition of the halide ion one can systematically alter the temperatures at which phase transitions can occur in order to evade the possibility of interconversion between polymorphs during processing or storage of materials.
|Number of pages||5|
|Early online date||3 Mar 2014|
|Publication status||Published - 14 Jul 2014|
- phase transition temperatures
- drug solid solutions
- phase transformations
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