Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

Hannes Horn, Cheng Cheng, RuAngelie Edrada-Ebel, Ute Hentschel, Usama Ramadan Abdelmohsen

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Abstract

Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.

Original languageEnglish
Pages (from-to)285-287
Number of pages3
JournalMarine Genomics
Volume24
Early online date20 Oct 2015
DOIs
Publication statusPublished - 1 Dec 2015

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Keywords

  • actinomycetes
  • Mediterranean sponges
  • secondary metabolism
  • draft genome
  • metabolic capacity

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