Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

Hannes Horn; Cheng Cheng; RuAngelie Edrada-Ebel; Ute Hentschel; Usama Ramadan Abdelmohsen

doi:10.1016/j.margen.2015.10.003

Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

Hannes Horn, Cheng Cheng, RuAngelie Edrada-Ebel, Ute Hentschel, Usama Ramadan Abdelmohsen^*

^*Corresponding author for this work

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

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Abstract

Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.

Original language	English
Pages (from-to)	285-287
Number of pages	3
Journal	Marine Genomics
Volume	24
Early online date	20 Oct 2015
DOIs	https://doi.org/10.1016/j.margen.2015.10.003
Publication status	Published - 1 Dec 2015

Keywords

actinomycetes
Mediterranean sponges
secondary metabolism
draft genome
metabolic capacity

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10.1016/j.margen.2015.10.003Licence: CC BY-NC-ND 4.0

Horn-etal-MarineGenomics-2015-genome-sequences-of-three-chemically-rich-actinomycetesFinal published version, 174 KBLicence: CC BY-NC-ND 4.0

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title = "Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges",

abstract = "Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.",

keywords = "actinomycetes, Mediterranean sponges, secondary metabolism, draft genome, metabolic capacity",

author = "Hannes Horn and Cheng Cheng and RuAngelie Edrada-Ebel and Ute Hentschel and Abdelmohsen, {Usama Ramadan}",

year = "2015",

month = dec,

day = "1",

doi = "10.1016/j.margen.2015.10.003",

language = "English",

volume = "24",

pages = "285--287",

journal = "Marine Genomics",

issn = "1874-7787",

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TY - JOUR

T1 - Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

AU - Horn, Hannes

AU - Cheng, Cheng

AU - Edrada-Ebel, RuAngelie

AU - Hentschel, Ute

AU - Abdelmohsen, Usama Ramadan

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.

AB - Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.

KW - actinomycetes

KW - Mediterranean sponges

KW - secondary metabolism

KW - draft genome

KW - metabolic capacity

UR - http://www.sciencedirect.com/science/journal/18747787

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U2 - 10.1016/j.margen.2015.10.003

DO - 10.1016/j.margen.2015.10.003

M3 - Article

SN - 1874-7787

VL - 24

SP - 285

EP - 287

JO - Marine Genomics

JF - Marine Genomics

ER -

Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

Abstract

Keywords

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SBT: SeaBioTech

Individual codes, GenBank accession numbers and GenBank accession links for Mediterranean sponges

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Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Projects

SBT: SeaBioTech

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Individual codes, GenBank accession numbers and GenBank accession links for Mediterranean sponges

Cite this