Abstract
Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.
| Language | English |
|---|---|
| Pages | 285-287 |
| Number of pages | 3 |
| Journal | Marine Genomics |
| Volume | 24 |
| Early online date | 20 Oct 2015 |
| DOIs | |
| Publication status | Published - 1 Dec 2015 |
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Keywords
- actinomycetes
- Mediterranean sponges
- secondary metabolism
- draft genome
- metabolic capacity
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Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges. / Horn, Hannes; Cheng, Cheng; Edrada-Ebel, RuAngelie; Hentschel, Ute; Abdelmohsen, Usama Ramadan.
In: Marine Genomics, Vol. 24, 01.12.2015, p. 285-287.Research output: Contribution to journal › Article
TY - JOUR
T1 - Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges
AU - Horn, Hannes
AU - Cheng, Cheng
AU - Edrada-Ebel, RuAngelie
AU - Hentschel, Ute
AU - Abdelmohsen, Usama Ramadan
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.
AB - Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes. Streptomyces sp. SBT349,. Nonomureae sp. SBT364, and. Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8. Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.
KW - actinomycetes
KW - Mediterranean sponges
KW - secondary metabolism
KW - draft genome
KW - metabolic capacity
UR - http://www.sciencedirect.com/science/journal/18747787
UR - http://www.scopus.com/inward/record.url?scp=84950266024&partnerID=8YFLogxK
U2 - 10.1016/j.margen.2015.10.003
DO - 10.1016/j.margen.2015.10.003
M3 - Article
VL - 24
SP - 285
EP - 287
JO - Marine Genomics
T2 - Marine Genomics
JF - Marine Genomics
SN - 1874-7787
ER -