Distributed 2D temperature sensing during nanoparticles assisted laser ablation by means of high-scattering fiber sensors

Zhannat Ashikbayeva, Arman Aitkulov, Madina Jelbuldina, Aizhan Issatayeva, Aidana Beisenova, Carlo Molardi, Paola Saccomandi, Wilfried Blanc, Vassilis J. Inglezakis, Daniele Tosi

Research output: Contribution to journalArticlepeer-review

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Abstract

The high demand in effective and minimally invasive cancer treatments, namely thermal ablation, leads to the demand for real-time multi-dimensional thermometry to evaluate the treatment effectiveness, which can be also assisted by the use of nanoparticles. We report the results of 20-nm gold and magnetic iron oxide nanoparticles-assisted laser ablation on a porcine liver phantom. The experimental set-up consisting of high-scattering nanoparticle-doped fibers was operated by means of a scattering–level multiplexing arrangement and interrogated via optical backscattered reflectometry, together with a solid-state laser diode operating at 980 nm. The multiplexed 2-dimensional fiber arrangement based on nanoparticle-doped fibers allowed an accurate superficial thermal map detected in real-time.

Original languageEnglish
Article number12593
Number of pages12
JournalScientific Reports
Volume10
DOIs
Publication statusPublished - 28 Jul 2020

Keywords

  • nanoparticles assisted laser ablation
  • optical backscattered reflectometry
  • solid-state laser diode

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