Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction

Greta Varchi, Christiane Kofink, David M. Lindsay, Alfredo Ricci, Paul Knochel

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.
Original languageEnglish
Pages (from-to)396-397
Number of pages2
JournalChemical Communications
Issue number3
Publication statusPublished - 14 Jan 2003


  • polyfunctional amino-substituted arylmagnesium reagents
  • iodine–magnesium exchange reaction

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