Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction

Greta Varchi; Christiane Kofink; David M. Lindsay; Alfredo Ricci; Paul  Knochel

doi:10.1039/b211115b

Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction

Greta Varchi, Christiane Kofink, David M. Lindsay, Alfredo Ricci, Paul Knochel

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

Original language	English
Pages (from-to)	396-397
Number of pages	2
Journal	Chemical Communications
Issue number	3
DOIs	https://doi.org/10.1039/b211115b
Publication status	Published - 14 Jan 2003

Keywords

polyfunctional amino-substituted arylmagnesium reagents
iodine–magnesium exchange reaction

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10.1039/b211115b

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title = "Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction",

abstract = "The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.",

keywords = "polyfunctional amino-substituted arylmagnesium reagents, iodine–magnesium exchange reaction",

author = "Greta Varchi and Christiane Kofink and Lindsay, {David M.} and Alfredo Ricci and Paul Knochel",

year = "2003",

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doi = "10.1039/b211115b",

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T1 - Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction

AU - Varchi, Greta

AU - Kofink, Christiane

AU - Lindsay, David M.

AU - Ricci, Alfredo

AU - Knochel, Paul

PY - 2003/1/14

Y1 - 2003/1/14

N2 - The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

AB - The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

KW - polyfunctional amino-substituted arylmagnesium reagents

KW - iodine–magnesium exchange reaction

U2 - 10.1039/b211115b

DO - 10.1039/b211115b

M3 - Article

SN - 1359-7345

SP - 396

EP - 397

JO - Chemical Communications

JF - Chemical Communications

IS - 3

ER -

Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodinetextendashmagnesium exchange reaction

Abstract

Keywords

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