Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata

Yao Wang, RuAngelie Edrada-Ebel, Nanzad Tsevegsurent, Jandirk Sendker, Manfred Braun, Victor Wray, Wenhan Lin, Peter Proksch

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.
Original languageEnglish
Pages (from-to)671-675
Number of pages4
JournalJournal of Natural Products
Volume72
Issue number4
DOIs
Publication statusPublished - Mar 2009

Keywords

  • dihydrostilbene derivatives
  • mongolian medicinal plant
  • drugs
  • pharmacology
  • scorzonera radiata

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