TY - JOUR
T1 - Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata
AU - Wang, Yao
AU - Edrada-Ebel, RuAngelie
AU - Tsevegsurent, Nanzad
AU - Sendker, Jandirk
AU - Braun, Manfred
AU - Wray, Victor
AU - Lin, Wenhan
AU - Proksch, Peter
PY - 2009/3
Y1 - 2009/3
N2 - Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.
AB - Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.
KW - dihydrostilbene derivatives
KW - mongolian medicinal plant
KW - drugs
KW - pharmacology
KW - scorzonera radiata
UR - http://dx.doi.org/10.1021/np800782f
U2 - 10.1021/np800782f
DO - 10.1021/np800782f
M3 - Article
SN - 0163-3864
VL - 72
SP - 671
EP - 675
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 4
ER -