Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives

Niamh Nic Daeid, Kathleen A. Savage, Donna Ramsay, Ciara Holland, Oliver B. Sutcliffe

Research output: Contribution to journalArticle

30 Citations (Scopus)


The prevalence of so-called 'legal high' drugs in forensic science drug casework has increased markedly in recent years. This has given rise to both legal and analytical challenges in the identification of these substances. The requirement for validated, reliable and rapid testing methodologies for these compounds is obvious. This work reports the analysis of sixteen synthesised cathinone derivatives encountered in casework using presumptive testing, thin layer chromatography and gas chromatography-mass spectrometry (GC-MS).

Original languageEnglish
Pages (from-to)22-31
Number of pages10
JournalScience and Justice
Issue number1
Early online date5 Sep 2013
Publication statusPublished - 31 Jan 2014


  • characterisation (NMR, FTIR)
  • GC-MS screen
  • legal high
  • triage

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