Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives

Niamh Nic Daeid, Kathleen A. Savage, Donna Ramsay, Ciara Holland, Oliver B. Sutcliffe

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The prevalence of so-called 'legal high' drugs in forensic science drug casework has increased markedly in recent years. This has given rise to both legal and analytical challenges in the identification of these substances. The requirement for validated, reliable and rapid testing methodologies for these compounds is obvious. This work reports the analysis of sixteen synthesised cathinone derivatives encountered in casework using presumptive testing, thin layer chromatography and gas chromatography-mass spectrometry (GC-MS).

LanguageEnglish
Pages22-31
Number of pages10
JournalScience and Justice
Volume54
Issue number1
Early online date5 Sep 2013
DOIs
Publication statusPublished - 31 Jan 2014

Fingerprint

Gas Chromatography-Mass Spectrometry
Forensic Sciences
Thin Layer Chromatography
Pharmaceutical Preparations
cathinone

Keywords

  • characterisation (NMR, FTIR)
  • GC-MS screen
  • legal high
  • triage

Cite this

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Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives. / Nic Daeid, Niamh; Savage, Kathleen A.; Ramsay, Donna; Holland, Ciara; Sutcliffe, Oliver B.

In: Science and Justice, Vol. 54, No. 1, 31.01.2014, p. 22-31.

Research output: Contribution to journalArticle

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