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Detection of miR-29a-3p, a microRNA associated with myocardial infarction, was achieved at a level of pg/L through the combination of three-dimensional paper-based microfluidics, colorimetric detection, and surface enhanced Raman scattering (SERS) analysis. The union of the paper-based device and the two analysis methods resulted in the production of a sensitive, reproducible and facile, point of care test (POCT), which paves the way for future implementation in the diagnosis of a range of diseases.
- myocardial infarction
- surface enhanced Raman scattering
Data for: "Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering"
Mabbott, S., Fernandes, S. C., Schechinger, M., Cote, G., Faulds, K., Mace, C. R., & Graham, D. (2019). Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering. Analyst. https://doi.org/10.1039/C9AN01748H