Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering

Samuel Mabbott, Syrena C. Fernandes, Monika Schechinger, Gerard Cote, Karen Faulds, Charles R. Mace, Duncan Graham

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Detection of miR-29a-3p, a microRNA associated with myocardial infarction, was achieved at a level of pg/L through the combination of three-dimensional paper-based microfluidics, colorimetric detection, and surface enhanced Raman scattering (SERS) analysis. The union of the paper-based device and the two analysis methods resulted in the production of a sensitive, reproducible and facile, point of care test (POCT), which paves the way for future implementation in the diagnosis of a range of diseases.
Original languageEnglish
JournalAnalyst
Early online date28 Nov 2019
DOIs
Publication statusE-pub ahead of print - 28 Nov 2019

Keywords

  • myocardial infarction
  • microfluidics
  • surface enhanced Raman scattering

Fingerprint Dive into the research topics of 'Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering'. Together they form a unique fingerprint.

  • Projects

    Cite this