Projects per year
amyloid's tyrosine excited at 279 nmand fluorescent in the window 240–450 nm. TRES has been used to demonstrate sturctural changes occuring on the nanosecond time scale after excitation which has significant advantages over using steady-state spectra.Wedemonstrate this by resolving the fluorescent species and revealing that beta-amyloid's monomers show very fast dielectric relaxation, and its oligomers display a substantial spectral shift due to dielectric relaxation, which gradually decreases when the oligomers become larger.
- Alzheimer's disease
FingerprintDive into the research topics of 'Detecting beta-amyloid aggregation from the time-resolved emission spectra'. Together they form a unique fingerprint.
- 1 Finished
1/08/08 → 31/01/12
Rolinski, O. (Creator), Alghamdi, A. A. M. (Creator), Vyshemirsky, V. (Creator) & Birch, D. (Creator), University of Strathclyde, 6 Mar 2018