Design and numerical simulation for the development of an expandable paediatric heart valve

Research output: Contribution to journalArticlepeer-review

1 Downloads (Pure)

Abstract

Current paediatric valve replacement options cannot compensate for somatic growth, leading to an obstruction of flow as the child outgrows the prosthesis. This often necessitates an increase in revision surgeries, leading to legacy issues into adulthood. An expandable valve concept was modelled with an inverse relationship between annulus size and height, to retain the leaflet geometry without requiring additional intervention. Parametric design modelling was used to define certain valve parameter aspect ratios in relation to the base radius, Rb, including commissural radius, Rc, valve height, H and coaptation height, x. Fluid-structure simulations were subsequently carried out using the Immersed Boundary method to radially compress down the fully expanded aortic valve whilst subjecting it to diastolic and systolic loading cycles. Leaflet radial displacements were analysed to determine if valve performance is likely to be compromised following compression. Work is ongoing to optimise valvular parameter design for the paediatric patient cohort.
Original languageEnglish
Number of pages12
JournalInternational Journal of Artificial Organs
Early online date10 Dec 2020
DOIs
Publication statusE-pub ahead of print - 10 Dec 2020

Keywords

  • paediatric valve replacement
  • prosthetic devices
  • valve parameter aspect ratio
  • aortic values
  • artificial kidney
  • apheresis and detoxification techniques
  • cardiovascular
  • computer simulations
  • paediatric cardiac surgery

Fingerprint Dive into the research topics of 'Design and numerical simulation for the development of an expandable paediatric heart valve'. Together they form a unique fingerprint.

Cite this