Dependence of ultrasonic and magnetic hyperthermia on the concentration of magnetic nanoparticles

K. Kaczmarek, T. Hornowski, R. Bielas, D. Żak, M. Timko, A. Józefczak

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Abstract

Hyperthermia treatment is the heating of tumor tissue up to temperatures between 41 ºC and 45 ºC, which trigger several physiological reactions in the body. Hyperthermia within tissue can be applied through various mechanisms. One of them is magnetic hyperthermia which uses superparamagnetic iron oxide nanoparticles (SPIONs) heated by an externally applied magnetic field. SPIONs can also be used as sonosensitizers in ultrasound hyperthermian increasing acoustic wave attenuation. The impact of SPION concentration on thermal effect during ultrasonic and magnetic hyperthermia was investigated in agar-gel phantom with added magnetite nanoparticles. The presence of nanoparticles in the tissue-mimicking phantom increases the thermal losses of ultrasound energy and temperature of the phantom.
Original languageEnglish
Pages (from-to)716-718
Number of pages3
JournalActa Physica Polonica A
Volume133
Issue number3
Publication statusPublished - 31 Mar 2018
EventThe European Conference Physics of Magnetism 2017 - Poznań, Poland
Duration: 26 Jun 201730 Jun 2017

Keywords

  • magnetic nanoparticles
  • magnetic hyperthermia

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