Dementia in Latin America: paving the way towards a regional action plan

Mario Alfredo Parra, LAC-CD (on behalf of)

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)
3 Downloads (Pure)


Regional challenges faced by Latin American and Caribbean countries (LACs) to fight dementia, such as heterogeneity, diversity, political instabilities, and socioeconomic disparities, can be addressed more effectively grounded in a collaborative setting based on the open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking and translational research) and align them to current global strategies to translate regional knowledge into actions with transformative power. Then, by characterizing genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions and mapping these to the above challenges, we provide the basic mosaics of knowledge that will pave the way towards a KtAF. We describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.
Original languageEnglish
Pages (from-to)295-313
Number of pages19
JournalAlzheimer's and Dementia
Issue number2
Early online date20 Nov 2020
Publication statusE-pub ahead of print - 20 Nov 2020


  • dementia
  • Latin America
  • evidence-based recommendation
  • knowledge to action framework
  • peidemiology
  • genetics
  • biomarkers
  • nonpharmacological interventions


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