Delivering natural products and biotherapeutics to improve drug efficacy

Mohammad A. Obeid, Mohammed M. Al Qaraghuli, Manal Alsaadi, Abdullah R. Alzahrani, Kanidta Niwasabutra, Valerie A. Ferro

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)
160 Downloads (Pure)


Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.
Original languageEnglish
Pages (from-to)947–956
Number of pages10
JournalTherapeutic Delivery
Issue number11
Early online date24 Oct 2017
Publication statusPublished - 1 Nov 2017


  • drug research
  • traditional medicine
  • drug discovery
  • biotherapeutics
  • drug delivery systems
  • natural products

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