Delivering natural products and biotherapeutics to improve drug efficacy

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.
LanguageEnglish
Pages947–956
Number of pages10
JournalTherapeutic Delivery
Volume8
Issue number11
Early online date24 Oct 2017
DOIs
Publication statusPublished - 1 Nov 2017

Fingerprint

Drug Industry
Drug Delivery Systems
Biological Products
Modern 1601-history
Drug Discovery
Drug Resistance
Pharmaceutical Preparations
Costs and Cost Analysis
Research

Keywords

  • drug research
  • traditional medicine
  • drug discovery
  • biotherapeutics
  • drug delivery systems
  • natural products

Cite this

@article{ffc250f596564ce8ad26837362741a5f,
title = "Delivering natural products and biotherapeutics to improve drug efficacy",
abstract = "Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.",
keywords = "drug research, traditional medicine, drug discovery, biotherapeutics, drug delivery systems, natural products",
author = "Obeid, {Mohammad A.} and {Al Qaraghuli}, {Mohammed M.} and Manal Alsaadi and Alzahrani, {Abdullah R.} and Kanidta Niwasabutra and Ferro, {Valerie A.}",
year = "2017",
month = "11",
day = "1",
doi = "10.4155/tde-2017-0060",
language = "English",
volume = "8",
pages = "947–956",
journal = "Therapeutic Delivery",
issn = "2041-5990",
number = "11",

}

Delivering natural products and biotherapeutics to improve drug efficacy. / Obeid, Mohammad A.; Al Qaraghuli, Mohammed M.; Alsaadi, Manal; Alzahrani, Abdullah R.; Niwasabutra, Kanidta; Ferro, Valerie A.

In: Therapeutic Delivery, Vol. 8, No. 11, 01.11.2017, p. 947–956.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Delivering natural products and biotherapeutics to improve drug efficacy

AU - Obeid, Mohammad A.

AU - Al Qaraghuli, Mohammed M.

AU - Alsaadi, Manal

AU - Alzahrani, Abdullah R.

AU - Niwasabutra, Kanidta

AU - Ferro, Valerie A.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.

AB - Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.

KW - drug research

KW - traditional medicine

KW - drug discovery

KW - biotherapeutics

KW - drug delivery systems

KW - natural products

UR - https://www.future-science.com/journal/tde

U2 - 10.4155/tde-2017-0060

DO - 10.4155/tde-2017-0060

M3 - Review article

VL - 8

SP - 947

EP - 956

JO - Therapeutic Delivery

T2 - Therapeutic Delivery

JF - Therapeutic Delivery

SN - 2041-5990

IS - 11

ER -