Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

E. Ritchie; M. Saka; C. MacKenzie; R.M. Drummond; C. Wheeler-Jones; T. Kanke; R.J. Plevin

doi:10.1038/sj.bjp.0707150

Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

E. Ritchie
, M. Saka
, C. MacKenzie
, R.M. Drummond
, C. Wheeler-Jones
, T. Kanke
, R.J. Plevin

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.

Original language	English
Pages (from-to)	1044-1054
Number of pages	10
Journal	British Journal of Pharmacology
Volume	150
DOIs	https://doi.org/10.1038/sj.bjp.0707150
Publication status	Published - 2007

Keywords

adenovirus
2-furoyl(2f)-LIGKV-OH
human umbilical vein
endothelial cells
inhibitory kappa
B kinase
nuclear factor
kappa B
proteinase-activated receptor

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10.1038/sj.bjp.0707150

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title = "Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase {\ss} in human endothelial cells",

abstract = "Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.",

keywords = "adenovirus, 2-furoyl(2f)-LIGKV-OH, human umbilical vein, endothelial cells, inhibitory kappa, B kinase, nuclear factor, kappa B, proteinase-activated receptor",

author = "E. Ritchie and M. Saka and C. MacKenzie and R.M. Drummond and C. Wheeler-Jones and T. Kanke and R.J. Plevin",

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journal = "British Journal of Pharmacology",

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T1 - Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

AU - Ritchie, E.

AU - Saka, M.

AU - MacKenzie, C.

AU - Drummond, R.M.

AU - Wheeler-Jones, C.

AU - Kanke, T.

AU - Plevin, R.J.

PY - 2007

Y1 - 2007

N2 - Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.

AB - Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.

KW - adenovirus

KW - 2-furoyl(2f)-LIGKV-OH

KW - human umbilical vein

KW - endothelial cells

KW - inhibitory kappa

KW - B kinase

KW - nuclear factor

KW - kappa B

KW - proteinase-activated receptor

UR - http://dx.doi.org/10.1038/sj.bjp.0707150

U2 - 10.1038/sj.bjp.0707150

DO - 10.1038/sj.bjp.0707150

M3 - Article

SN - 0007-1188

VL - 150

SP - 1044

EP - 1054

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

ER -

Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

Abstract

Keywords

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