Abstract
| Language | English |
|---|---|
| Title of host publication | IFMBE Proceedings |
| Editors | Ratko Magjarevic |
| Publisher | Springer |
| Pages | 1507-1510 |
| Number of pages | 4 |
| Volume | 31 |
| Edition | 6 |
| DOIs | |
| Publication status | Published - 2010 |
| Event | 6th world congress of biomechanics (WCB 2010) - , Singapore Duration: 1 Aug 2010 → 6 Aug 2010 |
Publication series
| Name | IFMBE Proceedings Series |
|---|---|
| Publisher | Springer |
| ISSN (Print) | 1680-0737 |
Conference
| Conference | 6th world congress of biomechanics (WCB 2010) |
|---|---|
| Country | Singapore |
| Period | 1/08/10 → 6/08/10 |
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Keywords
- atherosclerosis plaque
- stress analysis
- curvedness
Cite this
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Curvedness study on atherosclerosis plaques and its implications to plaque stress. / Gao, Hao; Long, Quan; Graves, Martin; Li, Zhiyong; Gillard, Jonathan.
IFMBE Proceedings. ed. / Ratko Magjarevic. Vol. 31 6. ed. Springer, 2010. p. 1507-1510 (IFMBE Proceedings Series).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book
TY - GEN
T1 - Curvedness study on atherosclerosis plaques and its implications to plaque stress
AU - Gao, Hao
AU - Long, Quan
AU - Graves, Martin
AU - Li, Zhiyong
AU - Gillard, Jonathan
PY - 2010
Y1 - 2010
N2 - Atherosclerosis plaque rupture has been considered to be a mechanical failure of the thin fibrous cap, resulted from extreme plaque stress. Plaque stress was affected by many factors from morphological features to biological abnormalities. In this study, geometrical factors (curvedness, fibrous cap thickness) were studied on assessing plaque vulnerability in comparison with stress analysis results obtained by fluid structure interaction from 20 human carotid atherosclerosis plaques. The results show that plaque surface curvedness could contribute to extreme stress level, especially in plaque shoulder region. General plaque stress distribution could be predicted by fibrous cap thickness and curvedness with multi-regression model. With more features included in the regression model, plaque stress could be easily calculated and used to assess plaque vulnerability.
AB - Atherosclerosis plaque rupture has been considered to be a mechanical failure of the thin fibrous cap, resulted from extreme plaque stress. Plaque stress was affected by many factors from morphological features to biological abnormalities. In this study, geometrical factors (curvedness, fibrous cap thickness) were studied on assessing plaque vulnerability in comparison with stress analysis results obtained by fluid structure interaction from 20 human carotid atherosclerosis plaques. The results show that plaque surface curvedness could contribute to extreme stress level, especially in plaque shoulder region. General plaque stress distribution could be predicted by fibrous cap thickness and curvedness with multi-regression model. With more features included in the regression model, plaque stress could be easily calculated and used to assess plaque vulnerability.
KW - atherosclerosis plaque
KW - stress analysis
KW - curvedness
U2 - 10.1007/978-3-642-14515-5_384
DO - 10.1007/978-3-642-14515-5_384
M3 - Conference contribution book
VL - 31
T3 - IFMBE Proceedings Series
SP - 1507
EP - 1510
BT - IFMBE Proceedings
A2 - Magjarevic, Ratko
PB - Springer
ER -