Abstract
| Language | English |
|---|---|
| Pages | 451-452 |
| Number of pages | 2 |
| Journal | Analytical Proceedings |
| Volume | 30 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 1 Nov 1993 |
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Keywords
- crystallisation
- kinetics
- crystal structure
- crystallization
- particle characterisation
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Crystallization kinetics : the role of particle characterisation. / Price, C. J.
In: Analytical Proceedings, Vol. 30, No. 11, 01.11.1993, p. 451-452.Research output: Contribution to journal › Article
TY - JOUR
T1 - Crystallization kinetics
T2 - Analytical Proceedings
AU - Price, C. J.
PY - 1993/11/1
Y1 - 1993/11/1
N2 - Kinetics are an important cornerstone of all industrial processes, including crystallization. An attempt must be made to maximize the production rate of in-specification (saleable) material at the minimum cost. Crystallization kinetics have a role to play in the optimization of the production of both single-crystal and multi-crystal products. Particle characterization has a vital dual role in determining that the product meets the specification, and in permitting the crystallization kinetics to be determined. Single-crystal products include: electronic substrate materials, such as Si and GaAs, materials with special optical propertiess, and complex biochemical species for crystal structure determination. Specifications can include: high purity, high perfection , specific facets, specific crystallographic orientation and crystal dimensions, all of which fall within the scope of particle characterization. Crystallization kinetics, particularly face-specific growth rates, are important since when the rate of crystal growth is increased most of the specified product properties are adversely affected. Multi-crystal products include the majority of solid-phase bulk chemical products: pharmaceuticals, agrochemicals, intermediates and commodity chemicals. Specifications often include crystal size distribution, purity, powder flow properties, dissolution rate, etc. Here the complex inter-relationships between supersaturation, hydrodynamics, feed purity, etc., are described by the crystallization kinetics and have a significant influence on the quality of the material produced.
AB - Kinetics are an important cornerstone of all industrial processes, including crystallization. An attempt must be made to maximize the production rate of in-specification (saleable) material at the minimum cost. Crystallization kinetics have a role to play in the optimization of the production of both single-crystal and multi-crystal products. Particle characterization has a vital dual role in determining that the product meets the specification, and in permitting the crystallization kinetics to be determined. Single-crystal products include: electronic substrate materials, such as Si and GaAs, materials with special optical propertiess, and complex biochemical species for crystal structure determination. Specifications can include: high purity, high perfection , specific facets, specific crystallographic orientation and crystal dimensions, all of which fall within the scope of particle characterization. Crystallization kinetics, particularly face-specific growth rates, are important since when the rate of crystal growth is increased most of the specified product properties are adversely affected. Multi-crystal products include the majority of solid-phase bulk chemical products: pharmaceuticals, agrochemicals, intermediates and commodity chemicals. Specifications often include crystal size distribution, purity, powder flow properties, dissolution rate, etc. Here the complex inter-relationships between supersaturation, hydrodynamics, feed purity, etc., are described by the crystallization kinetics and have a significant influence on the quality of the material produced.
KW - crystallisation
KW - kinetics
KW - crystal structure
KW - crystallization
KW - particle characterisation
U2 - 10.1039/AP9933000447
DO - 10.1039/AP9933000447
M3 - Article
VL - 30
SP - 451
EP - 452
JO - Analytical Proceedings
JF - Analytical Proceedings
SN - 0144-557X
IS - 11
ER -