Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity

Medicine & Life Sciences

• mouse AKR7A5 protein 100%
• AKR7A1 86%
• succinic semialdehyde 72%
• Substrate Specificity 43%
• Enzymes 21%
• Aldo-Keto Reductases 12%
• tartaric acid 11%
• Aflatoxins 10%
• Ketones 9%
• Aldehydes 9%
• NADP 8%
• Site-Directed Mutagenesis 8%
• Oxidoreductases 7%
• Catalytic Domain 6%
• Binding Sites 5%
• Alcohols 5%
• Amino Acids 5%
• Mutation 4%
• Liver 4%

Chemical Compounds

• Succinic Semialdehyde 65%
• Crystal Structure 19%
• Dialdehyde 9%
• Tartrate 9%
• Site-Directed Mutagenesis 8%
• Mutation 6%
• Binding Site 5%
• Aldehyde 5%
• Alcohol 4%
• Acid 2%