Projects per year
Abstract
The mixed solvated salt 4-(2-chlorodibenzo[b,f][1,4]oxazepin-11-yl)piperazin-1-ium acetate-acetic acid-cyclohexane (2/2/1), C17H17ClN3O+·C2H3O2-·C2H4O2·0.5C6H12, crystallizes with one molecule of protonated amoxapine (AXPN), an acetate anion and a molecule of acetic acid together with half a molecule of cyclohexane. In the centrosymmetric crystal, both enantiomers of the protonated AXPN molecule stack alternatively along [001]. Acetate anions connect the AXPN cations through N-H...O hydrogen bonding in the [010] direction, creating a sheet lying parallel to (100). The acetic acid molecules are linked to the acetate anions via O-H...O hydrogen bonds within the sheets. Within the sheets there are also a number of C-H...O hydrogen bonds present. The cyclohexane solvent molecules occupy the space between the sheets.
Original language | English |
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Pages (from-to) | 139-141 |
Number of pages | 3 |
Journal | Acta Crystallographica Section E: Structure Reports |
Volume | 71 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Feb 2015 |
Keywords
- amoxapine
- crystal structure
- hydrogen bonding
- mixed solvate
- oxaze-pine
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Dive into the research topics of 'Crystal structure of a mixed solvated form of amoxapine acetate'. Together they form a unique fingerprint.Projects
- 1 Finished
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Control and Prediction of the Organic Solid State: Translating the Technology (CPOSS Translation Award)
Florence, A. (Principal Investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/04/08 → 30/09/12
Project: Research