Corynephages: infections of the infectors

Vartul Sangal; Paul A. Hoskisson

doi:10.1007/978-94-007-7624-1_4

Corynephages: infections of the infectors

Vartul Sangal, Paul A. Hoskisson^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

27 Citations (Scopus)

Abstract

Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.

Original language	English
Title of host publication	Corynebacterium diphtheriae and Related Toxigenic Species
Subtitle of host publication	Genomics, Pathogenicity and Applications
Publisher	Springer Netherlands
Pages	67-81
Number of pages	15
ISBN (Electronic)	9789400776241
ISBN (Print)	9400776233, 9789400776234
DOIs	https://doi.org/10.1007/978-94-007-7624-1_4
Publication status	Published - 1 Aug 2014

Keywords

bacteriophage
Corynebacterium
Corynephage
Diphtheria
pathogenicity
phage conversion
toxigenic
toxin

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10.1007/978-94-007-7624-1_4

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AU - Hoskisson, Paul A.

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AB - Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.

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KW - Corynebacterium

KW - Corynephage

KW - Diphtheria

KW - pathogenicity

KW - phage conversion

KW - toxigenic

KW - toxin

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BT - Corynebacterium diphtheriae and Related Toxigenic Species

PB - Springer Netherlands

ER -

Corynephages: infections of the infectors

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Keywords

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