Copper-catalyzed coupling of hydroxylamines with aryl iodides.

Kerri L. Jones, Achim Porzelle, Adrian Hall, Michael D. Woodrow, Nicholas C. O. Tomkinson

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines, e.g., I, were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.
Original languageEnglish
Pages (from-to)797-800
Number of pages4
JournalOrganic Letters
Volume10
Issue number5
Early online date26 Jan 2008
DOIs
Publication statusPublished - 2008

Keywords

  • aryl iodides
  • copper-catalyzed N-arylation
  • aryl coupling partners

Fingerprint Dive into the research topics of 'Copper-catalyzed coupling of hydroxylamines with aryl iodides.'. Together they form a unique fingerprint.

  • Cite this