Cooperative, ion-sensitive co-assembly of tripeptide hydrogels

Yousef M. Abul-Haija, Gary G. Scott, Jugal Kishore Sahoo, Tell Tuttle, Rein V. Ulijn

Research output: Contribution to journalArticle

  • 9 Citations

Abstract

Peptide co-assembly is of interest for the development of functional supramolecular biomaterials. Herein, computational simulations were combined with experimental validation to aid the design and understanding of cooporative co-assembly of a
structure-forming tripeptide (FFD) and a functional copper-binding tripeptide (GHK) leading to hydrogel formation in response to complexation with copper ions.
LanguageEnglish
Pages9562-9565
Number of pages4
JournalChemical Communications
Early online date7 Aug 2017
DOIs
Publication statusE-pub ahead of print - 7 Aug 2017

Fingerprint

Hydrogels
Copper
Ions
Hydrogel
Biocompatible Materials
Complexation
Biomaterials
Peptides

Keywords

  • peptide co-assembly
  • functional supramolecular biomaterials
  • computational simulations
  • structure-forming tripeptide
  • copper-binding tripeptide
  • FFD
  • GHK
  • hydrogel formation
  • copper ions

Cite this

Abul-Haija, Yousef M. ; Scott, Gary G. ; Sahoo, Jugal Kishore ; Tuttle, Tell ; Ulijn, Rein V. / Cooperative, ion-sensitive co-assembly of tripeptide hydrogels. In: Chemical Communications. 2017 ; pp. 9562-9565.
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Cooperative, ion-sensitive co-assembly of tripeptide hydrogels. / Abul-Haija, Yousef M.; Scott, Gary G.; Sahoo, Jugal Kishore; Tuttle, Tell; Ulijn, Rein V.

In: Chemical Communications, 07.08.2017, p. 9562-9565.

Research output: Contribution to journalArticle

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AU - Abul-Haija, Yousef M.

AU - Scott, Gary G.

AU - Sahoo, Jugal Kishore

AU - Tuttle, Tell

AU - Ulijn, Rein V.

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KW - computational simulations

KW - structure-forming tripeptide

KW - copper-binding tripeptide

KW - FFD

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KW - hydrogel formation

KW - copper ions

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M3 - Article

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T2 - Chemical Communications

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