Several strong candidate genes and regions have been implicated in bipolar disorder (BP) and schizophrenia (SCZ) through linkage and association studies. These disorders have also recently been studied in genome-wide association studies (GWAS), identifying further putative candidate loci, albeit with lower levels of significance and reproducibility than in GWAS of other complex disorders.
- bipolar disorder
- chromosome mapping
- Pair 4
- genetic linkage
- genome-wide association study
- polymorphism, single nucleotide
- receptors, cell surface