Controlled delivery of calcium gated MthK channels into an on-chip bilayer lipid membrane for electrophysiology measurements

Michele Zagnoni, Mairi E. Sandison, Robert J. Wood, Peter L. Roach, Hywel Morgan

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

3 Citations (Scopus)

Abstract

On-chip biological systems, such as bilayer lipid membranes (BLMs) into which proteins can be artificially reconstituted, have the potential for highly sensitive biochemical detection, particularly when coupled to an electronic and/or optical read-out system. In this work, the on-chip delivery, activation and recording of calcium gated potassium channels were investigated.
Original languageEnglish
Title of host publicationMicro Total Analysis 2006
Subtitle of host publicationProceedings of μTAS 2006 Conference
EditorsTakehiko Kitamori, Hiroyuki Fujita, Shinji Hasebe
Place of PublicationTokyo
Pages1342-1344
Number of pages3
Volume2
Publication statusPublished - 5 Nov 2006
Event10th International Conference on Miniaturized Systems in Chemistry and Life Sciences - Tokyo, Japan
Duration: 5 Nov 20069 Nov 2006

Conference

Conference10th International Conference on Miniaturized Systems in Chemistry and Life Sciences
Abbreviated titleMicroTAS 2006
CountryJapan
CityTokyo
Period5/11/069/11/06

Keywords

  • bilayer lipid membranes
  • vesicle fusion
  • electrophysiology
  • on-chip delivery
  • biochemical detection
  • calcium gated potassium channels

Fingerprint Dive into the research topics of 'Controlled delivery of calcium gated MthK channels into an on-chip bilayer lipid membrane for electrophysiology measurements'. Together they form a unique fingerprint.

  • Cite this

    Zagnoni, M., Sandison, M. E., Wood, R. J., Roach, P. L., & Morgan, H. (2006). Controlled delivery of calcium gated MthK channels into an on-chip bilayer lipid membrane for electrophysiology measurements. In T. Kitamori, H. Fujita, & S. Hasebe (Eds.), Micro Total Analysis 2006: Proceedings of μTAS 2006 Conference (Vol. 2, pp. 1342-1344).