Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods

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2 Citations (Scopus)

Abstract

With the rapid development of tissue engineering and gene therapy, collagen-based biomaterials are frequently used as cell transplant devices; an example is bio-artificial skin substitutes [1-3]. In this study, we determined the effects of two different cell-seeding methods, monolayer and suspension seeding, on the rate of contraction of free-floating collagen and collagenglycosaminoglycan (GAG) gel matrices in vitro. 3T3 mouse fibroblasts were cultured in/on the matrices for up to 7 days.
Original languageEnglish
Pages (from-to)55-56
Number of pages1
JournalEuropean Cells and Materials
Volume4
Issue number2
Publication statusPublished - 2002

Keywords

  • tissue engineering
  • gene therapy
  • materials science
  • boengineering
  • cells

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