Continuous pharmaceutical crystallization from solution

Christopher J. Price

doi:10.1007/978-94-024-1117-1_19

Continuous pharmaceutical crystallization from solution

Christopher J. Price

Chemical And Process Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

The pharmaceutical industry has traditionally employed exclusively batch manufacturing for drug substances. The current trend is to explore continuous manufacturing; this chapter described the process by which a continuous pharmaceutical crystallization can be developed.

Original language	English
Title of host publication	Engineering Crystallography
Subtitle of host publication	From Molecule to Crystal to Functional Form
Editors	Kevin J. Roberts, Robert Docherty, Rui Tamura
Place of Publication	Dordrecht, The Netherlands
Publisher	Springer
Chapter	19
Pages	315-329
Number of pages	15
Edition	1st
ISBN (Print)	9789402411157, 9789402411188, 9789402411171
DOIs	https://doi.org/10.1007/978-94-024-1117-1_19
Publication status	Published - 28 Jul 2017
Event	NATO Advanced Study Institute on Molecules to Crystals to Powders: Understanding Structure Versus Function - Erice, Sicily, Italy Duration: 4 Jun 2015 → 14 Jun 2015

Course

Course	NATO Advanced Study Institute on Molecules to Crystals to Powders
Country/Territory	Italy
City	Sicily
Period	4/06/15 → 14/06/15

Keywords

continuous crystallization
pharmaceutical crystallization
process development
nucleation
growth
purification
crystal size distribution
consistent product quality

Access to Document

10.1007/978-94-024-1117-1_19

1 Finished

Transforming Industrial Crystallization by Sono-mechanical Manipulation of Crystal Surfaces
Price, C. J. (Fellow)
EPSRC (Engineering and Physical Sciences Research Council)
28/04/14 → 30/08/19
Project: Research Fellowship

1 Citations
2 Paper

Developing pharmaceutical continuous crystallization processes
Price, C. J., 2012.
Research output: Contribution to conference › Paper
Developing a multi-product pharmaceutical continuous crystallization capability
Price, C. J., 2011.
Research output: Contribution to conference › Paper

Cite this

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title = "Continuous pharmaceutical crystallization from solution",

abstract = "The pharmaceutical industry has traditionally employed exclusively batch manufacturing for drug substances. The current trend is to explore continuous manufacturing; this chapter described the process by which a continuous pharmaceutical crystallization can be developed.",

keywords = "continuous crystallization, pharmaceutical crystallization, process development, nucleation, growth, purification, crystal size distribution, consistent product quality",

author = "Price, {Christopher J.}",

year = "2017",

month = jul,

day = "28",

doi = "10.1007/978-94-024-1117-1_19",

language = "English",

isbn = "9789402411157",

pages = "315--329",

editor = "Roberts, {Kevin J.} and Robert Docherty and Rui Tamura",

booktitle = "Engineering Crystallography",

publisher = "Springer",

edition = "1st",

note = "NATO Advanced Study Institute on Molecules to Crystals to Powders : Understanding Structure Versus Function ; Conference date: 04-06-2015 Through 14-06-2015",

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Price, CJ 2017, Continuous pharmaceutical crystallization from solution. in KJ Roberts, R Docherty & R Tamura (eds), Engineering Crystallography: From Molecule to Crystal to Functional Form. 1st edn, Springer, Dordrecht, The Netherlands, pp. 315-329, NATO Advanced Study Institute on Molecules to Crystals to Powders, Sicily, Italy, 4/06/15. https://doi.org/10.1007/978-94-024-1117-1_19

TY - CHAP

T1 - Continuous pharmaceutical crystallization from solution

AU - Price, Christopher J.

PY - 2017/7/28

Y1 - 2017/7/28

N2 - The pharmaceutical industry has traditionally employed exclusively batch manufacturing for drug substances. The current trend is to explore continuous manufacturing; this chapter described the process by which a continuous pharmaceutical crystallization can be developed.

AB - The pharmaceutical industry has traditionally employed exclusively batch manufacturing for drug substances. The current trend is to explore continuous manufacturing; this chapter described the process by which a continuous pharmaceutical crystallization can be developed.

KW - continuous crystallization

KW - pharmaceutical crystallization

KW - process development

KW - nucleation

KW - growth

KW - purification

KW - crystal size distribution

KW - consistent product quality

U2 - 10.1007/978-94-024-1117-1_19

DO - 10.1007/978-94-024-1117-1_19

M3 - Chapter

SN - 9789402411157

SN - 9789402411188

SN - 9789402411171

SP - 315

EP - 329

BT - Engineering Crystallography

A2 - Roberts, Kevin J.

A2 - Docherty, Robert

A2 - Tamura, Rui

PB - Springer

CY - Dordrecht, The Netherlands

T2 - NATO Advanced Study Institute on Molecules to Crystals to Powders

Y2 - 4 June 2015 through 14 June 2015

ER -

Continuous pharmaceutical crystallization from solution

Abstract

Course

Keywords

Access to Document

Fingerprint

Projects

Transforming Industrial Crystallization by Sono-mechanical Manipulation of Crystal Surfaces

Research output

Developing pharmaceutical continuous crystallization processes

Developing a multi-product pharmaceutical continuous crystallization capability

Cite this