Construction of DNA architectures with RNA Hairpins

G. Mayer, Damian Ackermann, Nicole Kuhn, Michael Famulok

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Kissing complexes formed on the basis of highly specific noncanonical interactions of RNA hairpins can be harnessed for the controlled assembly of DNA nanoobjects. Two DNA minicircles, each equipped with a different RNA hairpin motif (see picture), mediate a tight and specific binding of the two circular DNA nanoobjects. These interactions may offer the possibility to construct DNA nanoobjects with increased complexity.
Original languageEnglish
Pages (from-to)971-973
Number of pages2
JournalAgewandte Chemie-International Edition
Volume47
Issue number5
DOIs
Publication statusPublished - Jan 2008

Keywords

  • DNA structures
  • hairpins
  • nanostructures
  • RNA structures

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