Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation

Robert M. Edkins; Elliott Hayden; Jonathan W. Steed; Katharina Fucke

doi:10.1039/c4cc10453f

Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation

Robert M. Edkins, Elliott Hayden, Jonathan W. Steed, Katharina Fucke

Pure And Applied Chemistry

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

Two tetrahydocarbazolone derivatives were found to show multiple unsolvated crystal forms. A persistent dimer motif was detected in solution by FTIR spectroscopy that is maintained in the kinetic crystal forms. Rationally introduced steric bulk induces the formation of a more stable catemeric form.

Original language	English
Pages (from-to)	5314-5317
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	25
DOIs	https://doi.org/10.1039/c4cc10453f
Publication status	Published - 28 Mar 2015

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Keywords

tetrahydrocarbazolone derivatives
crystal form nucleation
conserved hydrogen bonding

Cite this

Edkins, R. M., Hayden, E., Steed, J. W., & Fucke, K. (2015). Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation. Chemical Communications, 51(25), 5314-5317. https://doi.org/10.1039/c4cc10453f

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AU - Fucke, Katharina

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Access to Document

10.1039/c4cc10453f

Link to publication in Scopus