TY - JOUR
T1 - Computer-aided biophysical modeling
T2 - a quantitative approach to complex biological systems
AU - Milotti, Edoardo
AU - Vyshemirsky, Vladislav
AU - Sega, Michela
AU - Stella, Sabrina
AU - Dogo, Federico
AU - Chignola, Roberto
N1 - added volume
PY - 2013
Y1 - 2013
N2 - When dealing with the biophysics of tumors, analytical and numerical modeling tools have long been regarded as potentially useful but practically immature tools. Further developments could not just overturn this predicament, but lead to completely new perspectives in biology. Here we give an account of our own computational tool and how we have put it to good use, and we discuss a paradigmatic example to outline a path to making cell biology more quantitative and predictive.
AB - When dealing with the biophysics of tumors, analytical and numerical modeling tools have long been regarded as potentially useful but practically immature tools. Further developments could not just overturn this predicament, but lead to completely new perspectives in biology. Here we give an account of our own computational tool and how we have put it to good use, and we discuss a paradigmatic example to outline a path to making cell biology more quantitative and predictive.
KW - computer-aided
KW - biophysical modeling
KW - quantitative approach
KW - complex biological systems
UR - http://www.scopus.com/inward/record.url?scp=84887946514&partnerID=8YFLogxK
U2 - 10.1109/TCBB.2013.35
DO - 10.1109/TCBB.2013.35
M3 - Article
C2 - 23648589
SN - 1545-5963
VL - 10
SP - 805
EP - 810
JO - IEEE/ACM Transactions on Computational Biology and Bioinformatics
JF - IEEE/ACM Transactions on Computational Biology and Bioinformatics
IS - 3
ER -