Abstract
Previous studies have employed generic 3D-multiscale models to predict haemodynamic effects of the hybrid procedure in hypoplastic left heart syndrome. Patient-specific models, derived from image data, may allow a more clinically relevant model. However, such models require long computation times and employ internal pulmonary artery band [dint] dimension, which limits clinical application. Simpler, zero-dimensional models utilize external PAB diameters [dext] and provide rapid analysis, which may better guide intervention. This study compared 0-D and 3-D modelling from a single patient dataset and investigated the relationship dint versus dext and hemodynamic outputs of the two models. Optimum oxygen delivery defined at dint = 2 mm corresponded to dext = 3.1 mm and 3.4 mm when models were matched for cardiac output or systemic pressure, respectively. 0-D and 3-D models when matched for PAB dimension produced close equivalence of hemodynamics and ventricular energetics.
From this study we conclude that 0-D model can provide a valid alternative to 3D-multiscale in the hybrid–HLHS circulation.
From this study we conclude that 0-D model can provide a valid alternative to 3D-multiscale in the hybrid–HLHS circulation.
Original language | English |
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Pages (from-to) | 1549-1553 |
Number of pages | 5 |
Journal | Medical Engineering and Physics |
Volume | 36 |
Issue number | 11 |
Early online date | 6 Oct 2014 |
DOIs | |
Publication status | Published - Nov 2014 |
Keywords
- Paediatric surgery
- hypoplastic left heart
- modelling
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Terry Gourlay
- Health and Wellbeing
- Biomedical Engineering - Visiting Professor
Person: Visiting Professor