Complex biomolecular networks: challenges and opportunities

Complex biomolecular networks include a series of networked complex systems ranging from genomic and transcriptomic to proteomic and metabolomic ones. The use of the term ‘biological’ networks for this type of systems, which is common in the literature, is inappropriate due to the fact that biomolecular networks are a subset of the biological ones, which also include cellular, anatomical or functional networks. After the pioneering works in this area at the end of the 1990s there has been an explosion of results in the application of network techniques to discovering biologically meaningful properties of biomolecular systems.