Competitive strategies differentiate closely related species of marine actinobacteria

Nastassia V Patin, Katherine R Duncan, Pieter C Dorrestein, Paul R Jensen

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Although competition, niche partitioning, and spatial isolation have been used to describe the ecology and evolution of macro-organisms, it is less clear to what extent these principles account for the extraordinary levels of bacterial diversity observed in nature. Ecological interactions among bacteria are particularly challenging to address due to methodological limitations and uncertainties over how to recognize fundamental units of diversity and link them to the functional traits and evolutionary processes that led to their divergence. Here we show that two closely related marine actinomycete species can be differentiated based on competitive strategies. Using a direct challenge assay to investigate inhibitory interactions with members of the bacterial community, we observed a temporal difference in the onset of inhibition. The majority of inhibitory activity exhibited by Salinispora arenicola occurred early in its growth cycle and was linked to antibiotic production. In contrast, most inhibition by Salinispora tropica occurred later in the growth cycle and was more commonly linked to nutrient depletion or other sources. Comparative genomics support these differences, with S. arenicola containing nearly twice the number of secondary metabolite biosynthetic gene clusters as S. tropica, indicating a greater potential for secondary metabolite production. In contrast, S. tropica is enriched in gene clusters associated with the acquisition of growth-limiting nutrients such as iron. Coupled with differences in growth rates, the results reveal that S. arenicola uses interference competition at the expense of growth, whereas S. tropica preferentially employs a strategy of exploitation competition. The results support the ecological divergence of two co-occurring and closely related species of marine bacteria by providing evidence they have evolved fundamentally different strategies to compete in marine sediments.

LanguageEnglish
Pages478-90
Number of pages13
JournalISME Journal
Volume10
Issue number2
DOIs
Publication statusPublished - 29 Feb 2016

Fingerprint

Actinobacteria
multigene family
secondary metabolites
bacteria
secondary metabolite
nutrients
marine sediments
Growth
crossover interference
bacterial communities
Multigene Family
niches
uncertainty
divergence
antibiotics
iron
genomics
ecology
interference competition
bacterium

Keywords

  • actinobacteria
  • bacteria (microorganisms
  • salinispora arenicola
  • salinispora tropica

Cite this

Patin, Nastassia V ; Duncan, Katherine R ; Dorrestein, Pieter C ; Jensen, Paul R. / Competitive strategies differentiate closely related species of marine actinobacteria. In: ISME Journal. 2016 ; Vol. 10, No. 2. pp. 478-90.
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Competitive strategies differentiate closely related species of marine actinobacteria. / Patin, Nastassia V; Duncan, Katherine R; Dorrestein, Pieter C; Jensen, Paul R.

In: ISME Journal, Vol. 10, No. 2, 29.02.2016, p. 478-90.

Research output: Contribution to journalArticle

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